Drug intelligence / Profile preview

QingFeiYin

Development stage
Preclinical
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

QingFeiYin is a traditional Chinese herbal formula used primarily for the treatment of acute lung injury (ALI) and respiratory conditions characterized by inflammation and heat in the lungs. It is composed of multiple herbs with actions that include clearing lung heat, transforming phlegm, stopping coughs, detoxifying the lungs, and supporting overall respiratory health. The formula contains active compounds that target pathways related to inflammation, apoptosis (cell death), oxidative stress as well as MAPK and PI3K-Akt signaling pathways. These mechanisms are believed to underlie its therapeutic effects in conditions such as ALI. The specific composition may vary slightly between manufacturers but typically includes ingredients like Armeniacae Semen (Xing Ren), Fritillaria Bulbus (Chuan Bei Mu), Glycyrrhiza Radix (Gan Cao), Eriobotrya japonica leaf (Pi Pa Ye), Morus alba root bark (Sang Bai Pi), Platycodon Radix (Jie Geng), Schisandra Fructus (Wu Wei Zi), Tangerine Peel (Ju Hong) among others[1][2][7]. It is widely available in granule or capsule form from various TCM suppliers.

Brand names
QingFeiYinEight Herb Clear Lung DecoctionPi Pa Qing Fei YinXin Yi Qing Fei Yin
Other names
清肺飲QFY
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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