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Qinggan Jieyu Fang (清肝解郁方) is a traditional Chinese herbal formula used primarily for the treatment of conditions associated with liver qi stagnation and heat, such as migraine and related syndromes. It is composed of multiple herbs designed to "clear the liver" and "relieve depression" according to Traditional Chinese Medicine (TCM) theory. Clinical studies have evaluated its efficacy in reducing migraine symptoms, improving syndrome scores related to liver qi stagnation with heat, and enhancing quality of life measures compared to standard treatments[1]. The mechanism of action is based on TCM principles rather than a single molecular target; it likely involves modulation of neurotransmitter systems, anti-inflammatory effects, and regulation of vascular function.
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