Drug intelligence / Profile preview

Qinghai Univ. Rac1 compound Ano-6

Development stage
Preclinical
Lead developer
Qinghai University
01

Overview

Qinghai Univ. Rac1 compound Ano-6: sourced facts only. name: "A pull-down assay revealed that the interaction between Rac1 and its downstream effector protein PAK1 was inhibited by these compounds and that the compound Ano-6 exhibited substantial activity, with an inhibition rate of more than 90 %." [PMID:38833990]; target: "A pull-down assay revealed that the interaction between Rac1 and its downstream effector protein PAK1 was inhibited by these compounds and that the compound Ano-6 exhibited substantial activity, with an inhibition rate of more than 90 %." [PMID:38833990]; developer: "State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, 251 Ningda Road, Xining 810016, Qinghai, China; Department of Pharmacy, Medical College of Qinghai University, 16 Kunlun Road, Xining 810016, Qinghai, China." [PMID:38833990]; stage: "Four weeks of oral treatment with Ano-6 was well-tolerated in mice, and it induced a potential anti-tumour response in xenografts of MDA-MB-231 cells." [PMID:38833990]

02

Targets

RAC1 (Rac family small GTPase 1)

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