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Qinghua Quyu is a traditional Chinese medicine (TCM) formula primarily studied for its effects in the treatment of **ulcerative colitis**. It comprises multiple herbal components and is thought to exert therapeutic effects by activating the **Wnt/β-catenin signaling pathway**, promoting epithelial cell proliferation, and repairing the intestinal mucosal barrier. Experimental evidence indicates that it reduces weight loss and disease activity index in disease models, repairs tissue morphology, and promotes regeneration of the colonic epithelium. Its precise composition is not universally standardized but always contains multiple TCM herbs. The formulation is primarily used as a rectal instillation for local treatment of mild to moderate ulcerative colitis[1][4][9][10].
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