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Qingre Lijie external formula
- Development stage
- Unknown
- Lead developer
- Longhua Hospital Shanghai University of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
Qingre Lijie external formula is a Traditional Chinese Medicine (TCM) botanical preparation used topically to manage hand-foot skin reaction (HFSR) and hand-foot syndrome (HFS) in patients receiving targeted anticancer therapies, such as sorafenib. Developed primarily by researchers at Longhua Hospital, the formula is designed to clear heat and resolve dampness, addressing the erythema, edema, pain, and skin cracking associated with chemotherapy-induced skin toxicities. It is typically administered as a warm solution for soaking the hands and feet. Clinical evaluation has focused on its ability to reduce the grade of skin toxicity and delay the onset of severe symptoms, thereby supporting the continuation of primary oncological treatment.
- Other names
- Qingre Lijie decoctionQingre Lijie washQingre Lishi external formula
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