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Qingre Qiangyao Granules is a Traditional Chinese Medicine (TCM) therapeutic candidate developed by Beijing Jiayu Dexing Pharmaceutical Technology Development Co., Ltd. for the treatment of ankylosing spondylitis (AS). The formulation is designed based on TCM principles to clear heat, resolve dampness, and strengthen the kidneys and lower back, specifically targeting the damp-heat syndrome often associated with the active phase of AS. In clinical trials, it has been evaluated for its ability to reduce spinal pain, improve physical function, and lower inflammatory markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). The drug has progressed to Phase III clinical development in China, positioning it as a potential herbal alternative or adjunct to conventional therapies like NSAIDs or DMARDs for managing chronic spinal inflammation.
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