Drug intelligence / Profile preview

qingwenbaidu decoction

Development stage: Preclinical
Lead developer: 302 Hospital of the People's Liberation Army
Administration: Oral

Overview

Qingwen Baidu Decoction (QBD) is a classical traditional Chinese medicine (TCM) formula widely utilized for its heat-clearing, detoxifying, and anti-inflammatory properties. It is composed of multiple herbal ingredients, including Gypsum Fibrosum, Cornu Bubali, Radix Rehmanniae, Rhizoma Coptidis, Fructus Gardeniae, Radix Platycodonis, Radix Scutellariae, Rhizoma Anemarrhenae, Radix Paeoniae Rubra, Radix Scrophulariae, Fructus Forsythiae, Herba Lophatheri, Cortex Moutan Radicis, and Radix Glycyrrhizae. QBD has been investigated for its therapeutic potential in treating acute lung injury (ALI), sepsis, influenza, and other inflammatory or infectious conditions. During the 2014 West African Ebola outbreak, the 302 Military Hospital of China sponsored a prospective clinical study evaluating the efficacy and safety of Qingwen Baidu Decoction combined with Xuebijing Injection for the treatment of Ebola virus disease.

Other names: QBDQWBDQingwen Baidu DecoctionQingwen Baidu Yin

Targets

NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)STAT3 (Signal Transducer and Activator of Transcription 3)TLR4 (Toll-like receptor 4)TNFA (Tumor necrosis factor alpha (soluble))

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