Drug intelligence / Profile preview

Qingxin Zishen decoction

Development stage
Preclinical
Administration
Oral
01

Overview

Qingxin Zishen decoction (QZD) is a traditional Chinese medicine formulation used to clear heart heat and nourish kidney. It is prepared through regular decoction methods and typically administered as one dose per day, divided into two separate doses. It is a multi-herb formulation. QZD has been studied for its effects on various conditions, particularly related to ovarian function and perimenopausal syndrome. Research indicates it may improve ovarian reserve function, delay ovarian recession, improve perimenopausal syndrome symptoms, and regulate apoptotic pathways in ovarian tissue. Clinical trials have evaluated its efficacy for decreased ovarian function, perimenopausal syndrome, and effects on the heart-brain-gut axis.

Other names
QZD
02

Targets

CYCS (Cytochrome c)BAX (Apoptosis regulator BAX)CASP3 (Caspase-3)CASP9 (Caspase-9)APAF1 (Apoptotic protease-activating factor 1)

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