Drug intelligence / Profile preview

qingxuan zhike granule

Development stage
Unknown
Lead developer
Suzhong Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Qingxuan Zhike Granule is a Traditional Chinese Medicine (TCM) hospital preparation developed by the **Yunnan Provincial Hospital of Traditional Chinese Medicine**. It is formulated based on classical TCM principles to treat respiratory conditions characterized by "wind-heat" syndrome. The preparation is primarily indicated for the treatment of influenza, acute bronchitis, and upper respiratory tract infections, specifically targeting symptoms such as cough, fever, sore throat, and yellow sputum. Its pharmacological action is attributed to a combination of herbal ingredients—typically including Mulberry Leaf (*Morus alba*), Chrysanthemum, and Apricot Kernel—which collectively exert antitussive, anti-inflammatory, and mild antiviral effects. During public health emergencies, including the COVID-19 pandemic and seasonal influenza outbreaks, it has been included in regional treatment protocols in Yunnan Province as a recommended therapy for symptomatic relief.

Brand names
Qingxuan Zhike Granule
Other names
Qingxuan Zhike Keli清宣止咳颗粒
02

Targets

MAPK14 (p38 mitogen-activated protein kinase alpha)CHUK (IKKα)STAT3 (Signal Transducer and Activator of Transcription 3)ACE2 (Angiotensin-converting enzyme 2)AR (Adrenergic receptors)Mpro (3C-like proteinase of SARS-CoV-2)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)HSP90AA1 (Heat shock protein HSP90-alpha)ESR1 (ERα)AHR (Aryl hydrocarbon receptor)ALOX5 (Arachidonate 5-lipoxygenase)ABCA1 (ATP-binding cassette transporter A1)

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