Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Qingyi Huaji
- Development stage
- Phase 3
- Lead developer
- Fudan University Shanghai Cancer Center
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Qingyi Huaji is a traditional Chinese herbal medicine formula developed for the treatment of advanced pancreatic cancer. It has demonstrated efficacy in improving cancer-related symptoms, prolonging survival, and inhibiting tumor growth in preclinical and clinical studies. Its therapeutic effects are mediated through multiple mechanisms, including the down-regulation of Ski expression, modulation of the Notch signaling pathway by decreasing Hes-1 and Hey-1, inhibition of MAPK/ERK and PI3K/Akt/mTOR signaling pathways, reduction of inflammatory cytokines such as IL-6, IL-8, and TNF-alpha, and reprogramming of metabolism via the LINC00346-OMA1-ATF4 signaling pathway.
- Other names
- 清胰化积颗粒剂Qingyi Huaji FormulaQingyi Huaji decoctionQingyihuaji FormulaQingyiHuaji optimized formulaQingyi Huayi formulaQiyi Huaji
02
Targets
NANOG (Nanog Homeobox)HEY1 (Hairy/enhancer-of-split related with YRPW motif protein 1)SKI (SKI proto-oncogene)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IL-6 (Interleukin 6)OMA1-ATF4 (Mitochondrial metallopeptidase OMA1 - Activating transcription factor 4 signaling axis)HES1 (Hairy and Enhancer of Split 1 Protein)
Beyond the preview
Go deeper on Qingyi Huaji.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Qingyi Huaji.