Drug intelligence / Profile preview

qinjiao dihuang tongbi tang

Development stage
Preclinical
Administration
Oral
01

Overview

Qinjiao Dihuang Tongbi Tang is a Traditional Chinese Medicine (TCM) herbal decoction primarily used for the treatment of "Bi syndrome," which corresponds to inflammatory joint diseases such as rheumatoid arthritis and osteoarthritis, particularly those characterized by Yin deficiency and internal heat. The formula typically features *Gentiana macrophylla* (Qinjiao) and *Rehmannia glutinosa* (Dihuang) as its principal components. It functions by dispelling wind-dampness, clearing heat, and nourishing Yin and blood to alleviate joint pain, swelling, and stiffness. While primarily used in traditional clinical practice, modern pharmacological studies on its constituent herbs suggest anti-inflammatory, analgesic, and immunomodulatory effects, often mediated through the inhibition of pro-inflammatory cytokines.

Other names
秦艽地黄通痹汤Qinjiao Dihuang Tongbi Decoction
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)

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