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Qipian is a polyvalent bacterial lysate tablet developed by Qilu Pharmaceutical. It is composed of inactivated lysates from three bacterial species: *Staphylococcus epidermidis*, *Moraxella catarrhalis* (formerly known as *Neisseria catarrhalis*), and *Bacillus subtilis*. Primarily utilized as an immunomodulatory add-on therapy for pediatric asthma and recurrent respiratory tract infections (RTI), Qipian works by shifting the immune response from a Th2-dominant allergic profile toward a Th1-dominant profile. This mechanism helps to reduce airway inflammation and hyper-responsiveness. Additionally, the drug enhances the production of secretory and serum immunoglobulins, including IgA, IgG, and IgM, which provides prophylactic protection against the respiratory infections that frequently trigger asthma exacerbations.
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