Drug intelligence / Profile preview

Qishen Yiqi Diwan

Development stage
Unknown
Lead developer
Tasly Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Qishen Yiqi Diwan (also known as Qishen Yiqi Dripping Pills or QSYQ) is a patented traditional Chinese medicine (TCM) formula developed and manufactured by Tasly Pharmaceutical Group. It is composed of extracts from four main herbs: *Astragalus membranaceus* (Huangqi), *Salvia miltiorrhiza* (Danshen), *Panax notoginseng* (Sanqi), and *Dalbergia odorifera* (Jiangxiang). Approved by the China National Medical Products Administration (NMPA) in 2003, it is primarily indicated for the treatment of cardiovascular diseases, including coronary heart disease, myocardial infarction, and ischemic heart failure. It is also being evaluated for the prevention of acute exacerbations in chronic obstructive pulmonary disease (COPD). Qishen Yiqi Diwan works through multi-target mechanisms, including anti-inflammatory, anti-fibrotic, antioxidant, and cardioprotective pathways, improving cardiac function and microcirculation.

Brand names
Qishen Yiqi DiwanQishen Yiqi Dripping Pills
Other names
Qi Shen Yi Qi Di WanQiseng Yiqi DiwanQishen Yiqi Drop PillQishen Yiqi Drop PillsQishen Yiqi Dropping PillQishen Yiqi PillsQSYQ
02

Targets

ACE (Angiotensin Converting Enzyme)POSTN (Periostin protein)AGTR1 (Angiotensin II Type-1 receptor)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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