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Qizhi Tongfeng Granule
- Development stage
- Unknown
- Lead developer
- Beijing University of Chinese Medicine Fangshan Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Qizhi Tongfeng Granule is a Traditional Chinese Medicine (TCM) hospital preparation developed by the Fangshan Hospital Affiliated to Beijing University of Chinese Medicine for the treatment of refractory chronic gout. The formulation is designed to address the complex pathology of chronic gouty arthritis, particularly in patients who do not respond well to standard urate-lowering therapies. Its therapeutic effects include lowering serum uric acid levels and providing anti-inflammatory relief. Mechanistically, it is thought to inhibit xanthine oxidase activity and modulate the production of pro-inflammatory cytokines such as interleukin-1 beta (IL-1β), which is a key driver of gouty inflammation. The drug is currently utilized within the hospital's clinical practice and has been evaluated in Phase 2 clinical trials to further establish its efficacy and safety profile.
- Brand names
- Qizhi Tongfeng Granule
- Other names
- Qingzhi Tongfeng GranuleQingzhi Tongfeng Keli清脂痛风颗粒
02
Targets
XO (Xanthine Oxidoreductase)URAT1 (Uric Acid Transporter 1)IL1B (Interleukin-1 beta)
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