Drug intelligence / Profile preview

Qizhi Tongluo

Development stage
Phase 3
Lead developer
Shanxi Zhendong Pharmaceutical
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Qizhi Tongluo (Qi Zhi Tong Luo) is a traditional Chinese herbal medicine formulation composed of 26 different herbs. It is primarily used as an adjunct therapy for the sequelae of apoplexy (stroke), including symptoms such as hemiplegia, limb numbness, facial paralysis, language impairment, and trouble walking. The capsule has also been studied for its potential efficacy in treating vascular cognitive impairment and memory loss. Its mechanism of action is not fully elucidated but is believed to involve tonifying qi (vital energy), promoting blood circulation, and unblocking meridians according to traditional Chinese medicine theory. Chemical analysis has identified over 100 constituents including flavones, saponins, salvianolic acids, butylphthalides, anthraquinones, monoterpenoid glycosides, caffeoyl-quinic acids, coumarins, alkaloids and stilbenes[1][2][4]. Clinical studies have evaluated its safety and efficacy in improving cognitive function in patients with mild cognitive impairment related to vascular causes[1].

Brand names
Qizhi Tongluo Capsules
Other names
Qi Zhi Tong LuoQZTLQizhi Tongluo CapsuleQizhi Tongluo Capsules
02

Targets

IL-6 (Interleukin 6)VEGFA (Vascular endothelial growth factor A)TP53 (Cellular Tumor Antigen p53 R175H)

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