Drug intelligence / Profile preview

QL-926

Development stage
Preclinical
Lead developer
Shenzhen Qinglan Biotechnology
Modality
Small Molecules
Administration
Transdermal
01

Overview

QL-926 is a small molecule local anesthetic belonging to the amide class, currently under development by BioQingLam. It is designed for anesthesia and utilizes a proprietary transdermal delivery system consisting of a soluble microneedle patch. This technology allows for the delivery of the anesthetic through the skin's barrier via dissolving microneedles, potentially offering a less invasive alternative to traditional needle injections. As an amide-type anesthetic, QL-926 is expected to work by blocking voltage-gated sodium channels, thereby inhibiting the initiation and conduction of nerve impulses to provide localized pain relief. The candidate is currently in the Investigator-Initiated Trial (IIT) stage of development.

02

Targets

NaV (Voltage-gated sodium channels)

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