Drug intelligence / Profile preview

QLF32004

Development stage
Phase 1
Lead developer
Qilu Pharmaceutical
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Injection
01

Overview

QLF32004 is an investigational bispecific antibody developed as a class 1 biological drug for the treatment of advanced malignant solid tumors and B-cell malignant tumors. It is administered by injection and is currently being evaluated in early-phase clinical trials to determine its safety, tolerability, pharmacokinetics, and recommended dose for further studies. The precise mechanism of action has not been disclosed. The drug is being developed by Qilu Pharmaceutical and has not yet received regulatory approval in any country[1][2][3].

02

Targets

TGFB1 (Transforming growth factor Beta-1 proprotein)CD274 (Programmed cell death protein 1 ligand 1)

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