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QLS31903 is an investigational antibody therapy developed by Qilu Pharmaceutical for the treatment of advanced solid tumors. It is currently in Phase 1 clinical trials, where it is being evaluated for safety, tolerability, pharmacokinetics, immunogenicity, and preliminary efficacy in patients with advanced solid tumors. The trial includes a cohort specifically for patients whose tumors are positive for glypican-3 (GPC3), suggesting that GPC3 may be a target of this antibody. The drug is administered via injection (subcutaneous route). As of now, the precise mechanism of action has not been publicly disclosed[1][7][9].
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