Drug intelligence / Profile preview

QPX2014

Development stage
Phase 1
Lead developer
Qpex Biopharma
Modality
Small Molecules
Administration
Intravenous
01

Overview

QPX2014 is an investigational small molecule antibiotic developed by Qpex Biopharma for the treatment of bacterial infections, particularly those caused by multidrug-resistant organisms. It is being studied primarily as part of a fixed combination with the ultra-broad spectrum beta-lactamase inhibitor QPX7728. The primary indication under investigation is infectious diseases, targeting pathogens such as carbapenem-resistant Enterobacteriaceae and Acinetobacter baumannii, which are considered urgent threats due to their resistance profiles. The mechanism of action for QPX2014 is reported as a LACTB inhibitor. As of now, clinical development has reached Phase 1 in healthy volunteers via intravenous administration[1][2][3][5].

02

Targets

LACTB (Serine beta-lactamase-like protein LACTB, mitochondrial)

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