Quadriclear

Quadriclear is a topical combination cream developed and marketed by LYN-EDGE PHARMACEUTICALS, primarily indicated for the treatment of inflammatory skin conditions where secondary bacterial or fungal infections are present or suspected. The formulation leverages a quadruple action approach—providing anti-inflammatory, antipruritic, antibacterial, and antifungal effects. Its active ingredients typically include clobetasol propionate, a high-potency corticosteroid that reduces inflammation by activating glucocorticoid receptors; neomycin sulfate, an aminoglycoside antibiotic that inhibits bacterial protein synthesis by targeting the 30S ribosomal subunit; and miconazole nitrate, an imidazole antifungal that disrupts fungal cell membrane synthesis by inhibiting lanosterol 14-alpha demethylase. Quadriclear is commonly used to manage eczema, psoriasis, and various forms of dermatitis, particularly in regions like Nigeria where such broad-spectrum topical treatments are a mainstay of dermatological care.

Brand names

Quadriclear