Drug intelligence / Profile preview

quadrivalent Lactobacillus vaginal live capsule

Development stage: Unknown
Lead developer: Sichuan Yanyang Biotechnology
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Vaginal

Overview

Quadrivalent Lactobacillus vaginal live capsule is a live biotherapeutic product (LBP) developed by Sichuan Anaerobic Biotechnology Co., Ltd. for the treatment of bacterial vaginosis (BV). It is an intravaginal capsule containing four specific strains of live Lactobacillus bacteria. The therapy is designed to restore a healthy vaginal microbiome, which is typically dominated by Lactobacillus species in healthy individuals. By reintroducing these beneficial bacteria, the product helps maintain an acidic vaginal environment through the production of lactic acid, thereby inhibiting the overgrowth of anaerobic pathogens such as Gardnerella vaginalis. It also produces antimicrobial compounds like hydrogen peroxide and competes with pathogens for epithelial adhesion. The drug is currently undergoing Phase II clinical evaluation in China.

Other names: Vaginal Lactobacillus Quadruple Live Capsule阴道用四联乳杆菌活菌胶囊

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