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Drug intelligence / Profile preview
quadrivalent split-virion influenza vaccine
- Development stage
- Phase 4
- Lead developer
- Shenzhen Kangtai Biological Products
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
The 4-valent influenza vaccine (split) is a quadrivalent split-virion vaccine candidate being developed by Shenzhen Kangtai Biological Products (Shenzhen Kangde) for the prevention of seasonal influenza. As a quadrivalent vaccine, it is designed to provide broader protection than traditional trivalent vaccines by including antigens from four different influenza virus strains: two influenza A subtypes (typically H1N1 and H3N2) and two influenza B lineages (typically Victoria and Yamagata). The split-virion technology involves disrupting the virus with detergents to expose internal and surface antigens, which generally results in a vaccine that is highly immunogenic while maintaining a favorable safety profile. The candidate is currently in the preclinical/R&D stage of development.
- Other names
- 4-valent influenza vaccine4-Valent Influenza Vaccine (split)Quadrivalent Influenza VaccineQuadrivalent split-virion influenza vaccine
02
Targets
HA (Influenza virus hemagglutinin (quadrivalent))NeuraminidaseHA (Hemagglutinin)
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