quercetin pentaacetate

Quercetin pentaacetate is a **synthetic, pentaacetylated derivative of the natural flavonoid quercetin**. It demonstrates **diverse biological activities**, including **antioxidant, anti-inflammatory, antiviral, and anticancer properties**[4][5][8][10][13]. This compound shows potent *in vitro* inhibition of lipid peroxidation and scavenges radicals; it inhibits LPS-induced nitrite and PGE2 production, and downregulates iNOS and COX-2 expression in immune cells[4][10]. Notably, quercetin pentaacetate **blocks the adhesion of respiratory syncytial virus (RSV) to cell surfaces** by binding the viral F-protein with high affinity, impeding infection[5][8][9]. It shows **higher metabolic stability and reduced cytotoxicity versus quercetin**. Additional in vitro work shows antiproliferative effects against various cancer cell lines[4][10]. Research remains at the preclinical stage; development status for any human therapeutic indication is unreported.

Other names

PentaacetylquercetinQuercetin acetate3,3',4',5,7-Pentaacetoxyflavone3,3',4',5,7-Penta(acetyloxy)flavonePeracetylated Quercetin3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one2-(3,4-diacetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate[2-acetyloxy-4-(3,5,7-triacetyloxy-4-oxochromen-2-yl)phenyl] acetate