Drug intelligence / Profile preview

quercus macrocarpa pollen

Development stage
Unknown
Lead developer
ALK Abelló
Administration
Percutaneous, Intradermal, Subcutaneous
01

Overview

Quercus macrocarpa pollen is an allergenic extract derived from the pollen of the Burr Oak tree. It is primarily utilized as a diagnostic tool in clinical allergy testing, such as skin prick tests or intradermal tests, to identify individuals with IgE-mediated hypersensitivity to oak pollen. As a biologic allergenic extract, it contains specific proteins that, when introduced to a sensitized individual, cross-link allergen-specific Immunoglobulin E (IgE) on the surface of mast cells and basophils. This interaction triggers the release of inflammatory mediators like histamine, resulting in a measurable wheal-and-flare reaction. Beyond its diagnostic use, similar extracts are also employed in allergen immunotherapy (desensitization) to treat allergic rhinitis, allergic conjunctivitis, and asthma by inducing immunological tolerance over time.

Other names
Burr Oak pollen extractBur Oak pollenQuercus macrocarpa pollen extract
02

Targets

A. annua-specific IgE (Artemisia annua-specific immunoglobulin E)

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