quetiapine or olanzapine or risperidone or aripiprazole

This entry refers to a group of four atypical (second-generation) antipsychotic drugs: quetiapine, olanzapine, risperidone, and aripiprazole. These medications are primarily used for the treatment of schizophrenia, bipolar disorder, and other psychiatric conditions. They act mainly by modulating neurotransmitter activity in the brain—primarily dopamine D2 receptor antagonism (except for aripiprazole, which is a partial agonist at D2), as well as effects on serotonin receptors (notably 5-HT2A antagonism). Each drug has a unique receptor binding profile that influences its efficacy and side effect spectrum. Quetiapine is known for its sedative properties; olanzapine is associated with significant metabolic side effects; risperidone can cause hyperprolactinemia; and aripiprazole tends to have fewer metabolic adverse effects due to its partial agonist action at dopamine receptors[1][3][5].

Brand names

SeroquelZyprexaRisperdalAbilify

Other names

quetiapine fumarateolanzapine pamoaterisperidone tartratearipiprazole lauroxil