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Qufeng Gutong Ningjiaogao

Development stage: Unknown
Lead developer: China Academy of Chinese Medical Sciences
Administration: Topical

Overview

Qufeng Gutong Ningjiaogao is a traditional Chinese medicine (TCM) topical gel-paste (cataplasm) developed for the treatment of chronic musculoskeletal pain, specifically associated with knee osteoarthritis. It is formulated to address the TCM syndrome of wind-cold-dampness arthralgia, which involves symptoms like joint pain, stiffness, and sensitivity to cold or damp environments. The preparation is applied topically to the affected joint to alleviate pain and improve mobility. It is currently being evaluated in multicenter clinical studies sponsored by Wang Jing Hospital of the China Academy of Chinese Medical Sciences (CACMS).

Brand names: Qufeng Gutong Ningjiaogao
Other names: 祛风骨痛凝胶膏

Targets

FOS (Activator Protein 1)TLR4 (Toll-like receptor 4)IL-6 (Interleukin 6)NF-κBTNFA (Tumor necrosis factor alpha (soluble))IL1B (Interleukin-1 beta)MYD88 (Myeloid differentiation primary response protein MyD88)

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