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Quince oxymel, traditionally known as Sekanjabin-e Safarjali in Iranian medicine, is a compound herbal preparation made from the juice of the quince fruit (*Cydonia oblonga*), honey (or sugar), and vinegar. It is primarily used in Traditional Iranian Medicine (TIM) to treat gastrointestinal disorders and migraines, particularly those associated with gastric dysfunction (gastric migraines). The formulation leverages the antioxidant and anti-inflammatory properties of quince's polyphenolic compounds alongside the gastroprotective effects of the oxymel base. In clinical research, it has been studied as a preventive treatment for migraine attacks, where it is hypothesized to act through the gut-brain axis to stabilize digestive function and reduce the triggers for headache episodes.
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