Drug intelligence / Profile preview

Quinvaxem

Development stage
Phase 4
Lead developer
Johnson & Johnson
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Quinvaxem is a fully liquid, ready-to-use pentavalent combination vaccine indicated for active immunization of infants and young children against five serious diseases: diphtheria, tetanus, pertussis (whooping cough), hepatitis B, and invasive disease caused by *Haemophilus influenzae* type b. The vaccine contains diphtheria and tetanus toxoids, inactivated whole-cell *Bordetella pertussis* suspension, hepatitis B surface antigen (HBsAg), and *Haemophilus influenzae* type b conjugated oligosaccharide. It works by stimulating the immune system to produce antibodies against these pathogens without causing illness. Quinvaxem was the first ready-to-use pentavalent vaccine to receive WHO prequalification in 2006 and has played a significant role in global childhood immunization programs[3][4][1]. The primary indication is for routine infant immunization as part of national vaccination schedules.

Brand names
Quinvaxem
Other names
DTwP-HepB-Hib fully-liquid combined vaccine
02

Targets

Diphtheria toxinHBsAg (Hepatitis B surface antigen)

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