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Quitting Using Medication-Medical University of South Carolina-tobacco use disorder
- Development stage
- Preclinical
- Lead developer
- GSK
- Modality
- Small Molecules
- Administration
- Buccal, Transdermal
01
Overview
**Quitting using Medication** is an arm-level intervention label in the Medical University of South Carolina-sponsored STEPS trial, not a distinct proprietary drug or drug-development candidate. The intervention consists of combination nicotine replacement therapy using a transdermal nicotine patch for sustained nicotine delivery plus nicotine lozenges for as-needed relief of cravings, alongside brief smoking-cessation counseling, for adults in outpatient substance use disorder treatment who smoke cigarettes. ([cancer.gov](https://www.cancer.gov/research/participate/clinical-trials-search/v?id=NCT06922617))
- Other names
- Quitting using Medication
02
Targets
α4β2 nAChR (Nicotinic acetylcholine receptor alpha4 beta2 subtype)α6β2 nAChR (α6β2 nicotinic receptor)CHRNA7 (α7 nicotinic receptor)
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