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Qushi Huatan Recipe
- Development stage
- Preclinical
- Lead developer
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Qushi Huatan Recipe is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Guangdong Provincial Hospital of Chinese Medicine for the treatment of cardiovascular conditions, specifically coronary heart disease and angina pectoris. Based on the TCM theory of phlegm-dampness syndrome, the recipe is designed to alleviate chest pain and improve cardiac function by clearing metabolic debris and reducing fluid retention. Its pharmacological actions include the regulation of lipid profiles, reduction of pro-inflammatory cytokines such as TNF-alpha and IL-6, and improvement of vascular endothelial function. Clinical research at the developing institution has focused on its ability to stabilize atherosclerotic plaques and reduce the frequency of angina attacks in patients with metabolic comorbidities.
- Other names
- Qushi Huatan DecoctionQushi Huatan Fang祛湿化痰方
02
Targets
IL-6 (Interleukin 6)NF-κBGSK3 (Glycogen synthase kinase 3 beta)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)HIF1A (Hypoxia-inducible factor 1-alpha)TLR4 (Toll-like receptor 4)
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