Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
quzhuo tongbi formula
- Development stage
- Preclinical
- Lead developer
- Zhejiang Chinese Medical University
- Administration
- Oral
01
Overview
Quzhuo Tongbi Formula (QZTB/QZTBD) is an empirical traditional Chinese medicine prescription used for the prevention and treatment of acute gouty arthritis. It has demonstrated anti-inflammatory and analgesic effects in animal models of gouty arthritis induced by monosodium urate (MSU) crystals. The formula suppresses ankle swelling and synovial inflammation, alleviates acute attacks, and may help prevent recurrent attacks. Its mechanism involves reducing mRNA and protein levels of NLRP3 inflammasome components as well as decreasing production of inflammatory cytokines such as IL-1β and TNF-α in affected joints[1][2][3]. Additionally, QZTBD has been shown to restore gut microbiota balance and promote the production of short-chain fatty acids (SCFAs), which may contribute to its therapeutic effects[3]. The decoction is composed of multiple Chinese medicinal herbs.
- Other names
- Qu-Zhuo-Tong-BiQu-Zhuo-Tong-Bi FormulaQu-Zhuo-Tong-Bi Decoction
02
Targets
NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)TNFA (Tumor necrosis factor alpha (soluble))IL1B (Interleukin-1 beta)
Beyond the preview
Go deeper on quzhuo tongbi formula.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on quzhuo tongbi formula.