Drug intelligence / Profile preview

R-mandelic acid

Development stage
Unknown
Modality
Small Molecules
Administration
Topical, Oral
01

Overview

(R)-Mandelic acid is the R-enantiomer of mandelic acid, a hydroxycarboxylic (alpha-hydroxy) organic compound with the chemical formula C8H8O3. It is a colorless crystalline solid that is soluble in water and various organic solvents. Mandelic acids are used as intermediates in pharmaceutical synthesis and as active ingredients in dermatological products due to their antimicrobial properties. The R-enantiomer can be produced synthetically or resolved from racemic mixtures. In medicine, mandelic acids have been used for urinary tract infections because of their antibacterial activity and are also utilized in skincare for acne treatment and anti-aging effects[1][3]. The mechanism of action primarily involves disruption of bacterial cell wall synthesis (antimicrobial effect) and exfoliation via alpha hydroxy acid activity.

Other names
(r)-mandelic acidd-(-)-mandelic acidalpha-hydroxyphenylacetic acidphenylglycolic acidapricot acid
02

Targets

Desmosome (Keratinocyte/Corneocyte)

Beyond the preview

Go deeper on R-mandelic acid.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on R-mandelic acid.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call