Drug intelligence / Profile preview

Rabeloc

Development stage
Unknown
Lead developer
Cadila Pharmaceuticals
Modality
Small Molecules
Administration
Intravenous
01

Overview

Rabeloc is an intravenous formulation of rabeprazole sodium, a substituted benzimidazole proton pump inhibitor (PPI). Developed by Cadila Pharmaceuticals, it was the first intravenous rabeprazole formulation introduced globally. It works by specifically inhibiting the H+/K+-ATPase enzyme at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion. It is primarily indicated for conditions requiring rapid reduction of gastric acid production, such as upper gastrointestinal bleeding, severe refractory gastro-oesophageal reflux disease (GERD), stress-induced mucosal injury, and acid peptic disease (APD).

Brand names
RabelocRabeloc IV
Other names
rabeprazole sodium IVrabeprazole sodium injection
02

Targets

ATP4A (Potassium–transporting ATPase alpha chain 1)

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