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Drug intelligence / Profile preview
rabies prophylaxis
- Development stage
- Preclinical
- Lead developer
- Mediclone Biotech
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intramuscular, Intralesional
01
Overview
Rabies prophylaxis (DST-funded R&D project) is a preclinical-stage monoclonal antibody cocktail being developed by Mediclone Biotech for the post-exposure prophylaxis of rabies. Funded in part by the Department of Science and Technology (DST) of the Government of India, the project aims to develop an alternative to traditional equine-derived rabies immunoglobulin (ERIG) and human rabies immunoglobulin (HRIG). The therapeutic cocktail consists of monoclonal antibodies that target and neutralize the rabies virus, specifically binding to the rabies virus glycoprotein to prevent viral entry into host cells and subsequent central nervous system infection.
- Other names
- Anti-Rabies Monoclonal Antibody (MAb) cocktailAnti-Rabies Monoclonal Antibody cocktailmonoclonal rabies serum
02
Targets
RABV-G (Rabies virus glycoprotein)
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