Drug intelligence / Profile preview

rabies vaccine serum-free vero cell

Development stage
Phase 3
Lead developer
Sanofi
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Intradermal
01

Overview

A next-generation inactivated rabies vaccine produced using Vero cell culture technology in a serum-free medium. Developed primarily by Sanofi (as VRVg-2) and Ningbo Rong'an Biopharmaceutical, this vaccine is designed for both pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) of rabies. The serum-free manufacturing process aims to improve safety by eliminating animal-derived components and enhancing consistency compared to traditional Vero cell vaccines like Verorab. It works by inducing rabies virus neutralizing antibodies (RVNA) to provide immunity against the rabies virus.

Brand names
VerorabVax
Other names
Purified Vero Rabies Vaccine - Serum FreePVRV-SFserum-free Vero cell rabies vaccine
02

Targets

RABV-G (Rabies virus glycoprotein)

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