raclopride

Raclopride is a synthetic small molecule classified as a typical antipsychotic and acts as a selective antagonist at dopamine D2 receptors, with moderate selectivity for D3 receptors and much lower affinity for D4 and D1 receptors. It is primarily used in research settings, including clinical trials for Parkinson's disease, schizophrenia, and neuroimaging studies. Radiolabeled forms of raclopride (such as ^11C-raclopride) are widely used in positron emission tomography (PET) to assess dopamine receptor density and function in the brain. Its mechanism involves blocking the action of dopamine at the D2 receptor site, which can modulate psychotic symptoms or be used to study neurological disorders[1][2][3][4][5].

Other names

RaclopridaRaclopridumRaclopride C 11