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RAD011
- Development stage
- Discontinued
- Lead developer
- Radius Health
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
RAD011 is a pharmaceutical-grade synthetic cannabidiol (CBD) oral solution developed for the treatment of hyperphagia and related neuro-behavioral symptoms in Prader-Willi syndrome (PWS). It is manufactured using traditional pharmaceutical processes to ensure high purity and consistency. The drug is being investigated for its potential to reduce excessive appetite and improve irritability and overall behaviors in PWS patients. RAD011 has been assessed in over 150 patients across multiple indications and has potential utility in other neuro-endocrine or metabolic orphan diseases[4][5][6].
- Brand names
- Spectrum Therapeutics
- Other names
- Synthetic cannabidiol oral solutionCannabidiol oral solutionLab-made cannabidiol oral solution
02
Targets
CNR1 (Cannabinoid receptor 1)TRPV1 (Transient receptor potential cation channel subfamily V member 1)GPR55 (G protein-coupled receptor 55)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))
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