radiolabeled TRV130

Radiolabeled TRV130 refers to a form of the small molecule drug oliceridine (TRV130) that has been tagged with a radioactive isotope for research purposes. Oliceridine is a G protein-biased agonist at the μ-opioid receptor (MOR), developed to provide potent analgesia with reduced risk of opioid-related adverse effects such as respiratory depression and constipation compared to traditional opioids like morphine. The radiolabeled version is primarily used in preclinical or clinical studies to investigate pharmacokinetics, receptor binding characteristics, and tissue distribution. The parent compound acts by preferentially activating G-protein signaling over β-arrestin recruitment at the MOR[3][5][9].

Brand names

Olinvyk

Other names

oliceridineoliceridine hydrochlorideOLINVYKTRV130 HClTRV-130 HClTRV 130 HCl