Drug intelligence / Profile preview

radix aucklandiae

Development stage
Phase 4
Administration
Oral
01

Overview

Radix Aucklandiae is the dried root of Aucklandia lappa Decne., commonly known as Mu Xiang in Chinese medicine. It has a long history of use in traditional East Asian medicine for promoting the movement of Qi (vital energy), alleviating pain, and treating various gastrointestinal disorders such as indigestion, abdominal fullness, bloating, diarrhea, and dysentery. The herb contains bioactive sesquiterpenes like costunolide and dehydrocostus lactone that contribute to its pharmacological effects. Modern research supports its anti-inflammatory properties—particularly through inhibition of NF-κB signaling—and demonstrates efficacy in reducing chemotherapy-induced intestinal mucositis by protecting intestinal epithelial cells and suppressing proinflammatory cytokines (IL-1β, IL-6, TNF-α). Radix Aucklandiae also exhibits antimicrobial activity against several pathogenic bacteria and fungi. In addition to digestive health benefits (including protection against gastric ulcers), it is used for pain relief associated with Qi stagnation throughout the body[1][2][3][4][5][7].

Brand names
Qust al-HindiKuthKushtha
Other names
mu xiangcostus rootaucklandia rootsaussurea costuswood aromatic root
02

Targets

Nuclear factor kappa-light-chain-enhancer of activated B cells pathway proteinsIL1B (Interleukin-1 beta)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))

Beyond the preview

Go deeper on radix aucklandiae.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on radix aucklandiae.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call