Drug intelligence / Profile preview

RAG-24

Development stage
Preclinical
Lead developer
Ractigen Therapeutics
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration
Subcutaneous
01

Overview

RAG-24 is a small activating RNA (saRNA) therapeutic candidate being developed by Ractigen Therapeutics for the treatment of obesity and related metabolic disorders. It utilizes the RNA activation (RNAa) mechanism to target gene regulatory domains and increase the expression of a specific, undisclosed endogenous therapeutic gene within adipose tissue. The drug is delivered using Ractigen's proprietary LiCO™ (lipid-conjugated oligonucleotide) technology, which facilitates targeted delivery to fat cells. RAG-24 is administered via subcutaneous injection and is currently in the discovery stage of development.

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