rapacuronium

Rapacuronium is a synthetic, nondepolarizing aminosteroid neuromuscular blocking agent that was used as an adjunct to general anesthesia to facilitate tracheal intubation and provide skeletal muscle relaxation during surgical procedures. It acts by antagonizing the muscarinic acetylcholine receptor M2 and blocks neuromuscular transmission at the motor endplate. Rapacuronium has a rapid onset of action and short-to-intermediate duration, with pharmacological properties similar to other steroidal neuromuscular blockers such as vecuronium and rocuronium. The drug was withdrawn from the market in 2001 due to reports of fatal bronchospasm[1][2][4][6].

Brand names

Raplon

Other names

rapacuronium bromiderapacuronium ion