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RAPT Therapeutics GCN2 compound 39: sourced facts only. name: "In mice, compound 39 engages GCN2 at levels ≥80% with an oral dose of 15 mg/kg BID." [PMID:36127295]; target: "In mice, compound 39 engages GCN2 at levels ≥80% with an oral dose of 15 mg/kg BID." [PMID:36127295]; developer: "RAPT Therapeutics, 561 Eccles Avenue, South San Francisco, California94080, United States." [PMID:36127295]; stage: "In the LL2 syngeneic mouse model, compound 39 demonstrates significant tumor growth inhibition (TGI) as a single agent." [PMID:36127295]
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