Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
RAS70 peptide
- Development stage
- Preclinical
- Lead developer
- V.A. Almazov Federal Center for Heart, Blood and Endocrinology
- Modality
- Peptides
- Administration
- Intravenous, Topical
01
Overview
RAS70 peptide is a 17-mer chimeric peptide designed to target membrane-bound heat shock protein 70 (mHsp70), which is selectively overexpressed on the plasma membrane of malignant brain tumors (such as glioblastoma) and brain metastases, but absent in normal tissues. It was developed by conjugating the 14-mer mHsp70-targeting peptide TKD (TKDNNLLGRFELSG) with the tripeptide RGD to enhance its bioavailability and blood-brain barrier (BBB) penetration. When conjugated to a fluorophore (such as Cy7.5), RAS70 serves as a diagnostic imaging agent for intraoperative fluorescence-guided surgery to delineate tumor margins. It is also being investigated as a potential carrier for targeted drug delivery.
- Other names
- RAS70RAS-70RAS 70RAS70-Cy5RAS-70-Cy5RAS 70-Cy5RAS70-Cy7.5RAS-70-Cy7.5RAS 70-Cy7.5RAS70-sCy5RAS-70-sCy5RAS 70-sCy5RAS70-sCy7.5RAS-70-sCy7.5RAS 70-sCy7.5
02
Targets
HSP70 (Heat shock protein 70)αVβ3 (Integrin αVβ3)
Beyond the preview
Go deeper on RAS70 peptide.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on RAS70 peptide.