Drug intelligence / Profile preview

RAU 018

Development stage: Preclinical
Modality: Small Molecules

Overview

RAU 018 is a novel aminonaphthoquinone derivative investigated for its potential as a therapeutic agent against various cancers. In preclinical studies, it has demonstrated cytotoxic, anti-angiogenic, and anti-metastatic effects on breast cancer cells (MCF-7 and MDA-MB-231), osteosarcoma cells (MG-63), and endometrial cancer cells (HEC-1A). Its efficacy is particularly noted when combined with curcumin, suggesting a synergistic effect in inhibiting cancer progression.

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