rauwolfia vomitoria extract

Rauwolfia vomitoria extract is a botanical preparation derived from the root, bark, or leaf of the Rauwolfia vomitoria plant, which is native to West Africa and used in both traditional and experimental medicine settings. The extract contains several phytochemicals, including alkaloids (such as reserpine, reserpinine, deserpidine, ajmalicine, and ajmaline), saponins, flavonoids, cardiac glycosides, phytosterols, vitamin E, lupeol, and vaccenic acid[2][3][7]. It possesses diverse pharmacological activities, including antihypertensive (blood pressure lowering), antiproliferative (notably for benign prostatic hyperplasia), antimicrobial, anti-inflammatory, immunomodulatory, antioxidant, and antitumor/cancer potential[1][2][5][8][10]. Mechanistically, it is reported to suppress androgen receptor signaling and related pathways in models of benign prostatic hyperplasia, reduce proliferation markers, and decrease steroid 5α-reductase 1 expression[1]. The extract also demonstrates significant antioxidant properties, likely due to its phenolic content[8]. Rauwolfia vomitoria extract is distinguishable from single-compound drugs like reserpine, as it contains a complex mixture of bioactive constituents.

Other names

rauwolfia vomitoria leaf extractrauwolfia vomitoria root extractrauwolfia vomitoria bark extractrauwolfia vomitoria (as an extract/preparation)rauvolfia vomitoria extract