Drug intelligence / Profile preview

RBLP

Development stage
Preclinical
Lead developer
ReBio Technologies
Modality
Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intravitreal
01

Overview

RBLP is a sustained-release formulation of latanoprost being developed by ReBio Technologies for the treatment of mild-to-moderate primary open-angle glaucoma. It utilizes the proprietary SiSu® technology platform, a resorbable polymer system designed for long-term, steady release of therapeutics within the eye. Administered via intravitreal injection approximately twice a year, RBLP aims to improve patient compliance and maintain consistent intraocular pressure reduction compared to traditional daily eye drops. The polymer scaffold is designed to safely dissolve once the drug release is complete, addressing the challenges of frequent dosing in chronic ocular conditions.

02

Targets

PTGFR (Prostaglandin F2 alpha receptor)

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