Drug intelligence / Profile preview

RBM-005

Development stage
Unknown
Lead developer
Ribomic
Modality
RNA Aptamers → RNA Therapeutics → Nucleic Acid Therapeutics, DNA Aptamers → DNA Therapeutics → Nucleic Acid Therapeutics
Administration
Topical
01

Overview

RBM-005 is an investigational RNA aptamer developed by Ribomic Inc. that specifically targets and inhibits Interleukin-17A (IL-17A). IL-17A is a pro-inflammatory cytokine that plays a central role in the pathogenesis of various autoimmune and inflammatory conditions, most notably psoriasis. By binding to IL-17A with high affinity and specificity, RBM-005 prevents the cytokine from interacting with its receptor, thereby modulating the downstream inflammatory signaling pathways. The drug is designed for topical administration to minimize systemic side effects while effectively treating localized inflammatory lesions, offering a potential alternative to systemic monoclonal antibody therapies.

Other names
anti-IL-17A RNA aptameranti-IL17A RNA aptameranti-IL 17A RNA aptamer
02

Targets

IL17RA (IL-17RA)

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