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RC-08 is a small molecule drug candidate that acts as an inhibitor of HPK1 (hematopoietic progenitor kinase 1), also known as mitogen-activated protein kinase kinase kinase kinase 1. It is being developed primarily for the treatment of neoplasms, with a focus on solid tumors. The drug was initially developed by Taizhou Hongyun Pharmaceutical and, as of April 2025, remains in preclinical development. By inhibiting HPK1, RC-08 aims to modulate immune signaling pathways relevant to cancer therapy[1].
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