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RC-121
- Development stage
- Unknown
- Lead developer
- Tulane University
- Modality
- Peptides
- Administration
- Subcutaneous
01
Overview
RC-121 is a synthetic octapeptide somatostatin analog developed for its potential antineoplastic properties. It acts as an agonist at somatostatin receptors, leading to the inhibition of growth hormone and prolactin secretion, and potentially interfering with the action of various growth factors. In experimental models, it has been studied as an adjunct to luteinizing hormone-releasing hormone (LHRH) agonists to enhance the suppression of prostate cancer growth. Structurally, it is closely related to vapreotide (RC-160), differing only by the presence of a C-terminal threonine residue instead of tryptophan.
- Other names
- D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH-2D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH 2
02
Targets
SSTR5 (Somatostatin receptor 5)SSTR2 (Somatostatin receptor type 2)
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