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rdGCM-1013 is a preclinical gene therapy candidate developed by Gencellmed for aesthetic applications, specifically targeting wrinkle care. The therapy utilizes a replication-defective Herpes Simplex Virus type 1 (HSV-1) viral vector to deliver therapeutic genetic material to the skin. By leveraging the large cargo capacity and natural skin-cell infectivity of HSV-1, while ensuring safety through the removal of replication-essential genes, rdGCM-1013 is designed to provide localized treatment for skin rejuvenation. The specific therapeutic gene and molecular target have not been publicly disclosed by the developer.
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